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药片的抗冲击性能

Support for pharmaceutical tablet impact testing
Support for pharmaceutical tablet impact testing

常见的药用片剂通常会进行包衣处理,以方便吞咽、实现药物缓释、便于识别及品牌标识。包衣还能保护内部药品免受光照、温度、湿度和载荷等不利环境因素的影响,从而延长产品保质期。尤其在生产和包装过程中,片剂包衣易受冲击而受损。

冲击试验可以为制造商提供研发新型涂层材料或工艺所需的性能数据,从而创造价值。一旦确定了合适的产品,制造商即可利用冲击性能测试的基准数据实施质量控制计划,实现持续的工艺验证。

一台 INSTRON 9440 落锤冲击试验系统,配备小载荷压电传感器冲头(0.45 kN 或 4.5 kN), ½ 英寸半球形或平面冲头插件,以及 Bluehill Impact 软件 是药丸和药片测试的理想选择。对于工装,我们建议使用可以轻松固定在工作台面上的坚硬、平坦的金属板。

该冲击测试方案特别适用于测定药片抗冲击性能特征,例如批次一致性、失效点或初始损伤点。这些特性可能与产品所用包衣材料相关。通过了解包衣如何增强或削弱药片强度,可据此实施改进措施以优化产品性能。

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